A Rare Case of a Second-Degree Chemical Burn due to Successive Contacts of Acidic Wart Removal Solution and Paint Solution

Main Article Content

Lysia Matius Gressida
Myra Sylvina Amri
Ahmad Fawzy
Ismiralda Oke Putranti

Abstract

Introduction: Chemical burns are an uncommon form of burn injury, accounting for 2.1% to 6.5% of all burn centre admissions. We presented one rare case of a second degree chemical burn due to successive contacts of acidic wart removal solution and paint mixture solution.


Case: A 38-year-old male with chemical burn on both feet due to reckless usage of a self-purchased wart removal solution, and accidental contact with paint mixture solution. Our surgeon author diagnosed a superficial partial thickness (second-degree) chemical burn on this patient, and performed surgical debridement followed by hyaluronic-enhanced silver sulfadiazine topical dressing to provide antimicrobial protection to the wound and topical petrolatum-based ointment to maintain moist environment for the wound and the periwound. Our team also gave Ceftaroline, a cephalosporin for serious infections of the skin and tissues below the skin, intravenously.


Result: One day after the surgical procedure, the wound dimensions were slightly more extensive than the initial size due to extensive debridement and necrotomy. All wounds produced no or minimal exudate, showed no slough nor pus inside the granulation area, and no swelling nor maceration in the periwound area. The fifth day after the surgical procedure, the wound on the lateral side of patient’s right foot was almost completely covered by epithelialization. The wound on the sole of patient’s right foot was about 70-80% covered by epithelialization, and the wound on the sole of patient’s left foot was also about 70% covered by epithelialization.


Discussion: Topical solution for wart removal consists of many chemicals agents (i.e. salicylic acid and acetic acid) and its application should strongly be under guidance and monitoring by physician due to its potential to harm human bodies and trigger chemical burn injury in varying degrees. Paint mixture is usually safe, risks no or minimal harms when in contact with skin, however it can provide a more difficult scenario and consequently a more extensive cleansing during the wound debridement procedure. Immediate decontamination and adequate dilution through massive irrigation is a major determinant of burn severity after chemical injury. Application of 1% silver sulfadiazine topical antibiotics enhanced with 0.2% hyaluronic acid for moisturizer displayed significant improvement for the burn wound healing.


Conclusion: Knowing exactly what type of chemical substance in contact with the skin and tissues that caused the chemical burn injury is as equally important as the comprehensive management itself. For acidic burn injuries, a proper and sometimes extensive necrotomy procedure is mandatory to provide a good tissue regeneration.

Article Details

How to Cite
Gressida, L. M., Myra Sylvina Amri, Ahmad Fawzy, & Ismiralda Oke Putranti. (2023). A Rare Case of a Second-Degree Chemical Burn due to Successive Contacts of Acidic Wart Removal Solution and Paint Solution. International Journal of Medical Science and Clinical Research Studies, 3(4), 670–678. https://doi.org/10.47191/ijmscrs/v3-i4-18
Section
Articles

References

I. American Burn Association. Advanced Burn Life Support Course: Chemical Burn. [Internet]. American Burn Association. American Burn Association; 2018 [cited 2023Mar14]. Available from: http://ameriburn.org/wp-content/uploads/2019/08/2018-abls-providermanual.pdf

II. Friedstat J, Brown DA, Levi B. Chemical, electrical, and radiation injuries. Clinics in Plastic Surgery. 2017;44(3):657–69.

III. Wardhana A, Basuki A, Prameswara AD, Rizkita DN, Andarie AA, Canintika AF. The epidemiology of burns in Indonesia’s National Referral Burn Center from 2013 to 2015. Burns Open. 2017;1(2):67–73.

IV. Koyro KI, Bingoel AS, Bucher F, Vogt PM. Burn guidelines—an international comparison. European Burn Journal. 2021;2(3):125–39.

V. Palao R, Monge I, Ruiz M, Barret JP. Chemical burns: Pathophysiology and treatment. Burns. 2010;36(3):295–304.

VI. British Burn Association First Aid Clinical Practice Guidelines [Internet]. [cited 2023Mar14]. Available from: https://www.britishburnassociation.org/wp-content/uploads/2017/06/BBA-First-Aid-Guideline-24.9.18.pdf

VII. Tan T, Wong DSY. Chemical burns revisited: What is the most appropriate method of decontamination? Burns. 2015;41(4):761–3.

VIII. Hemington-Gorse S, Pellard S, Wilson-Jones N, Potokar T. Foot burns: Epidemiology and management. Burns. 2007;33(8):1041–5.

IX. Tiong WHC, Kelly EJ. Salicylic acid burn induced by wart remover: A report of two cases. Burns. 2009;35(1):139–40.

X. Selvaraj DR, Adjei B, Farooq AL-NAHHAS O, Kamil L, Yonjan I. A rare case of a chemical burn: Dithranol with salicylic acid. World Journal of Plastic Surgery. 2022;11(1):138–40.

XI. Balagué N, Vostrel P, Beaulieu J-Y, van Aaken J. Third degree formic acid chemical burn in the treatment of a hand wart: A case report and review of the literature. SpringerPlus. 2014;3(1).

XII. Akelma H, Karahan ZA. Rare chemical burns: Review of the literature. International Wound Journal. 2019;16(6):1330–8.

XIII. Yoo J-H, Roh S-G, Lee N-H, Yang K-M, Moon J-H. A case report of a chemical burn due to the misuse of glacial acetic acid. Journal of Plastic, Reconstructive Aesthetic Surgery. 2010;63(12).

XIV. Ahmadi H, Durrant CAT, Sarraf KM, Jawad M. Chemical burns: A review. Current Anaesthesia & Critical Care. 2008;19(5-6):282–6.

XV. Seisenbaeva GA, Fromell K, Vinogradov VV, Terekhov AN, Pakhomov AV, Nilsson B, et al. Dispersion of tio2 nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins. Scientific Reports. 2017;7(1).

XVI. Chick LR, Borah G. Calcium carbonate gel therapy for hydrofluoric acid burns of the hand. Plast Reconstr Surg. 1990 Nov;86(5):935-40.

XVII. Beroual K, Agabou A, Abdeldjelil MC, Boutaghane N, Haouam S, Hamdi-Pacha Y. Evaluation of crude flaxseed (Linum usitatissimum L) oil in burn wound healing in New Zealand rabbits. Afr J Tradit Complement Altern Med. 2017 Mar 1;14(3):280-286.

XVIII. Occupational Health Guidelines for Chemical Hazards (81-123) [Internet]. Centers for Disease Control and Prevention. Centers for Disease Control and Prevention; 2014 [cited 2023Mar14]. Available from:https://www.cdc.gov/niosh/docs/81-123/default.html

XIX. Irawan H, Yasa KP. A case report of diabetic foot ulcer underwent an autolytic debridement using hydrogel and hydrocellular foam combination. Bali Medical Journal. 2017;6(3):93.

XX. Fox CL Jr. Silver sulfadiazine--a new topical therapy for Pseudomonas in burns. Therapy of Pseudomonas infection in burns. Arch Surg. 1968 Feb;96(2):184-8.

XXI. Withers JN. Control of pseudomonas infections in burns with silver sulfadiazine. Hawaii Med J. 1970 Mar-Apr;29(4):298-300.

XXII. Dalmedico MM, Meier MJ, Felix JV, Pott FS, Petz Fde F, Santos MC. Hyaluronic acid covers in burn treatment: a systematic review. Rev Esc Enferm USP. 2016 May-Jun;50(3):522-8. English, Portuguese.

XXIII. Miyazaki Y, Asano M, Uchino T, Kagawa Y. [Development of a Breathable Protective Ointment for Moisture-associated Skin Damage]. Yakugaku Zasshi. 2019;139(10):1281-1284. Japanese.

XXIV. Duplessis C, Crum-Cianflone NF. Ceftaroline: A New Cephalosporin with Activity against Methicillin-Resistant Staphylococcus aureus (MRSA). Clin Med Rev Ther. 2011 Feb 10;3:a2466.

XXV. Goldstein EJ, Citron DM, Merriam CV, Tyrrell KL. Comparative in vitro activity of ceftaroline, ceftaroline-avibactam, and other antimicrobial agents against aerobic and anaerobic bacteria cultured from infected diabetic foot wounds. Diagn Microbiol Infect Dis. 2013 Jul;76(3):347-51

Most read articles by the same author(s)